Pulse Pressure and Antihypertensive Agents
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چکیده
منابع مشابه
Pulse pressure and antihypertensive agents.
Pulse Pressure and Antihypertensive Agents To the Editor: In their subanalysis of the LIFE study,1 the authors conclude that they “show superior protection against stroke in patients treated with losartan when compared with atenolol . . . This difference may be related to specific effects of angiotensin type 1 receptor antagonism . . . beyond blood BP reduction.” The authors do not consider the...
متن کاملPulse pressure changes with six classes of antihypertensive agents in a randomized, controlled trial.
Pulse pressure has been more strongly associated with cardiovascular outcomes, especially myocardial infarction and heart failure, than has systolic, diastolic, or mean arterial pressure in a variety of populations. Little is known, however, of the comparative effects of various classes of antihypertensive agents on pulse pressure. In retrospective analyses of the Veterans Affairs Single-Drug T...
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BACKGROUND The objective of this study was to assess whether antihypertensive treatment affects the predictive power of brachial pulse pressure. METHODS Data from the First National Health and Nutrition Examination Survey Epidemiologic Follow Up Study were used to conduct Cox regression analyses. There were 487 cardiovascular disease (CVD) and 348 coronary heart disease (CHD) deaths during an...
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Fostamatinib is a tyrosine kinase inhibitor with activity against spleen tyrosine kinase which has completed clinical trials for patients with rheumatoid arthritis. In clinical studies fostamatinib treatment was associated with a small elevation of systemic arterial blood pressure (BP), a similar finding to that seen with other kinase inhibitors, especially those that inhibit VEGFR2 signaling. ...
متن کاملAmbulatory blood pressure monitoring in clinical trials with antihypertensive agents.
Ambulatory blood pressure monitoring (ABPM) is being used increasingly for the evaluation of antihypertensive agents in clinical trials. In this brief review several aspects of ABPM are discussed. In particular, attention is paid to the extent to which ABPM is subject to a placebo response and the extent to which the sample size of the study population can be reduced with this type of measureme...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2005
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.0000179215.13289.55